Living with treatment-resistant depression (TRD) can feel like an uphill battle, impacting every aspect of life and making even daily tasks overwhelming. However, there’s new hope with Spravato® (esketamine) nasal spray. This innovative, FDA-approved treatment is specifically designed for individuals who haven’t found success with traditional antidepressants. Delivered under medical supervision, Spravato® works differently from standard medications, targeting areas of the brain linked to mood and depression. For many, it’s providing a much-needed path to relief and offering a chance to reclaim their lives.
Spravato® stands out from other antidepressant treatments because of how it works. Instead of targeting serotonin, dopamine, or norepinephrine like most medications, Spravato® focuses on the NMDA receptor in the brain. This stimulates the release of glutamate, a key neurotransmitter that helps improve brain connectivity and mood regulation. The result? Faster relief—often within hours or days—compared to the weeks traditional antidepressants can take.
Spravato® is administered as a nasal spray in a certified healthcare facility. Each session takes about two hours, starting with the nasal spray dose followed by observation. This monitoring period is crucial to ensure patient safety and to manage potential side effects, such as dizziness or dissociation. The treatment is paired with an oral antidepressant to maximize its effectiveness.
Spravato® is specifically designed for adults with treatment-resistant depression—those who have tried at least two other antidepressants without significant improvement. Because it’s a controlled substance, it’s only available through certified clinics that follow strict safety protocols. If you’ve been struggling with depression and haven’t found relief, Spravato® could be a life-changing option.
Many patients report feeling a sense of hope and improvement after starting Spravato®. Its unique mechanism offers a new path for those who have felt stuck with limited options. While it’s not a cure, it can be a powerful tool for managing symptoms and improving quality of life.
If you or a loved one is living with treatment-resistant depression, McMonigle Neurology Associates is here to help. As a certified provider of Spravato® nasal spray, we offer compassionate, expert care to guide you through this innovative treatment.
Take the first step toward relief today. Contact McMonigle Neurology Associates to learn more about eligibility, the treatment process, and how Spravato® can help you regain control of your mental health. Let us support you in your journey to a brighter future.